WebJul 25, 2024 · In geometrical isomer nomenclature, the prefix cis- and trans- are used to identify which side of the double bond the similar atoms are found. The cis- prefix is from the Latin meaning "on this side". In this case, the chlorine atoms are on the same side of the carbon-carbon double bond. This isomer is called cis-1,2-dichloroethene. WebFeb 5, 2024 · Isomerism in complex ions Complexes can show two types of stereoisomerism: cis-trans isomerism and optical isomerism Ni NH3 Cl H3N Cl Ni Cl NH3 H3N Cl ... Cisplatin can also prevent the replication of healthy cells by bonding on to healthy DNA which may lead to unwanted side effects like hair loss. Society needs to
The effect of geometric isomerism on the anticancer activity of …
WebCisplatin (cis-diamminedichloroplatinum(II)) is one of the most commonly used anticancer agents. It is administered intravenously, and on its way into the cell it can interact with blood proteins1and other macromolecules. WebAug 15, 2024 · CIS/TRANS isomers have different biological properties. Cis-platin has clinical importance in the treatment of ovarian and testicular cancers. The biological mechanism of the drug's action was long suspected to involve binding of the platinum by … polyester waffle weave blankets
Isomer - Wikipedia
WebCis-trans isomerism Stereoisomerism occurs when substances have the same molecular formula, but a different arrangement of their atoms in space. Cis-trans isomerism is one type of this isomerism. It applies to: … WebFeb 27, 2024 · Pyriplatin, cis -diammine (pyridine)chloroplatinum ( ii ), a monofunctional, cationic platinum ( ii) compound, displayed a spectrum of activity that differed from that of any of the clinically approved platinum drugs. 6 However, the overall potency of pyriplatin was much less than that of cisplatin in all cancer cell lines tested. WebCisplatin is used as an anti-cancer drug because it can bind to the DNA of rapidly growing cells and prevent replication. The trans form of this chemical is not as effective at binding to the DNA. Fac and Mer Stereoisomers When three identical ligands occupy one face of an octahedron, the isomer is said to be facial, or fac. polyester waffle weave fabric